A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen

A genome-wide ethyl-N-nitrosourea (ENU) mutagenesis screen in mice was performed to identify novel regulators of erythropoiesis. Here, we describe a mouse line, RBC16, which harbours a dominantly inherited mutation in the Cpox gene, responsible for production of the haem biosynthesis enzyme, copropo...

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Detalles Bibliográficos
Autores principales: Conway, Ashlee J., Brown, Fiona C., Fullinfaw, Robert O., Kile, Benjamin T., Jane, Stephen M., Curtis, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560062/
https://www.ncbi.nlm.nih.gov/pubmed/28600349
http://dx.doi.org/10.1242/dmm.029116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560062/
https://www.ncbi.nlm.nih.gov/pubmed/28600349
http://dx.doi.org/10.1242/dmm.029116

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