Cargando…
Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo
The gastric epithelium consists of tubular glandular units, each containing several differentiated cell types, and populations of stem cells, which enable the stomach to secrete the acid, mucus and various digestive enzymes required for its function. Very little is known about which cell signalling...
Autores principales: | Flanagan, Dustin J., Barker, Nick, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby J., Vincan, Elizabeth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560064/ https://www.ncbi.nlm.nih.gov/pubmed/28600348 http://dx.doi.org/10.1242/dmm.029876 |
Ejemplares similares
-
Frizzled7: A Promising Achilles’ Heel for Targeting the Wnt Receptor Complex to Treat Cancer
por: Phesse, Toby, et al.
Publicado: (2016) -
Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5(+) Stem Cells
por: Flanagan, Dustin J., et al.
Publicado: (2015) -
The Function of Lgr5(+) Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo
por: Flanagan, Dustin, et al.
Publicado: (2019) -
Wnt Signalling in Gastrointestinal Epithelial Stem Cells
por: Flanagan, Dustin J., et al.
Publicado: (2018) -
Targeting Wnt Signaling for the Treatment of Gastric Cancer
por: Koushyar, Sarah, et al.
Publicado: (2020)