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Iterative expansion microscopy
We recently discovered it was possible to physically magnify preserved biological specimens by embedding them in a densely crosslinked polyelectrolyte gel, anchoring key labels or biomolecules to the gel, mechanically homogenizing the specimen, and then swelling the gel-specimen composite by ~4.5x i...
Autores principales: | Chang, Jae-Byum, Chen, Fei, Yoon, Young-Gyu, Jung, Erica E., Babcock, Hazen, Kang, Jeong Seuk, Asano, Shoh, Suk, Ho-Jun, Pak, Nikita, Tillberg, Paul W., Wassie, Asmamaw, Cai, Dawen, Boyden, Edward S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560071/ https://www.ncbi.nlm.nih.gov/pubmed/28417997 http://dx.doi.org/10.1038/nmeth.4261 |
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