Cargando…

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

PURPOSE: Transgenic mice overexpressing serum retinol-binding protein (RBP4-Tg) develop progressive retinal degeneration, characterized by microglia activation, yet the precise mechanisms underlying retinal degeneration are unclear. Previous studies showed RBP4-Tg mice have normal ocular retinoid le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Mei, Phelps, Eric, Balangue, Michael J., Dockins, Aaron, Moiseyev, Gennadiy, Shin, Younghwa, Kane, Shelley, Otalora, Laura, Ma, Jian-Xing, Farjo, Rafal, Farjo, Krysten M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560100/ https://www.ncbi.nlm.nih.gov/pubmed/28813718 http://dx.doi.org/10.1167/iovs.17-22107

Ejemplares similares

Optimised expression and purification of RBP4 and preparation of anti‐RBP4 monoclonal antibody
por: Li, Hui, et al.
Publicado: (2021)

Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4
por: Du, Mei, et al.
Publicado: (2017)

Hepatocytes Are the Principal Source of Circulating RBP4 in Mice
por: Thompson, Spencer J., et al.
Publicado: (2017)

Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes
por: Liu, Haitao, et al.
Publicado: (2016)

Plasma RBP4 Level in Association with Body Composition, Metabolic Profile, STRA6 and RBP4 Gene Polymorphisms in Obese Romanian Children
por: Boaghi, Anastasia, et al.
Publicado: (2020)

RBP-J and ITAM crosstalk
por: Zhao, Baohong
Publicado: (2015)

Retinal Vascular Plexuses Are Unequally Affected in Canine Inherited Retinal Degenerations
por: Ripolles-Garcia, Ana, et al.
Publicado: (2022)

Association of RBP4 Genotype with Phenotypic Reproductive Traits of Sows
por: Marantidis, A., et al.
Publicado: (2016)

Adipokine RBP4 drives ovarian cancer cell migration
por: Wang, Yanyan, et al.
Publicado: (2018)

Biological Functions of RBP4 and Its Relevance for Human Diseases
por: Steinhoff, Julia S., et al.
Publicado: (2021)

Retinal Degeneration Caused by Ago2 Disruption
por: Chen, Xue-Jiao, et al.
Publicado: (2021)

Noninvasive Ophthalmic Imaging Measures Retinal Degeneration and Vision Deficits in Ndufs4(−/−) Mouse Model of Mitochondrial Complex I Deficiency
por: Avrutsky, Maria I., et al.
Publicado: (2022)

Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations
por: Foote, Katharina G., et al.
Publicado: (2019)

Noninvasive Electrical Stimulation Improves Photoreceptor Survival and Retinal Function in Mice with Inherited Photoreceptor Degeneration
por: Yu, Honghua, et al.
Publicado: (2020)

Characterization of RBP9 and RBP10, two developmentally regulated RNA-binding proteins in Trypanosoma brucei
por: De Pablos, Luis Miguel, et al.
Publicado: (2017)

Identification of the Avian RBP7 Gene as a New Adipose-Specific Gene and RBP7 Promoter-Driven GFP Expression in Adipose Tissue of Transgenic Quail
por: Ahn, Jinsoo, et al.
Publicado: (2015)

Vision Recovery and Connectivity by Fetal Retinal Sheet Transplantation in an Immunodeficient Retinal Degenerate Rat Model
por: Seiler, Magdalene J., et al.
Publicado: (2017)

Top Cited Session: the best of RBP
por: Quevedo, João, et al.
Publicado: (2018)

Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment
por: Li, Xiaomeng, et al.
Publicado: (2020)

The transcription factor RBP-J is essential for retinal cell differentiation and lamination
por: Zheng, Min-Hua, et al.
Publicado: (2009)

An RBP4 promoter polymorphism increases risk of type 2 diabetes
por: van Hoek, M., et al.
Publicado: (2008)

A Genetic Polymorphism in RBP4 Is Associated with Coronary Artery Disease
por: Wan, Ke, et al.
Publicado: (2014)

Interleukin-1β Downregulates RBP4 Secretion in Human Adipocytes
por: Kotnik, Primoz, et al.
Publicado: (2013)

RBP4 and THBS2 are serum biomarkers for diagnosis of colorectal cancer
por: Fei, Weiqiang, et al.
Publicado: (2017)

Involvement of RBP4 in Diabetic Atherosclerosis and the Role of Vitamin D Intervention
por: Zhou, Wan, et al.
Publicado: (2018)

Cbl downregulation increases RBP4 expression in adipocytes of female mice
por: Ameen, Gulizar Issa, et al.
Publicado: (2017)

Outer retinal corrugations in late-onset retinal degeneration: a diagnostic finding demonstrated with multimodal imaging
por: Duncan, Holly Joan, et al.
Publicado: (2023)

The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice
por: Nahomi, Rooban B., et al.
Publicado: (2018)

RasV12 Expression in Microglia Initiates Retinal Inflammation and Induces Photoreceptor Degeneration
por: Moriuchi, Yuta, et al.
Publicado: (2020)

Optimization and Validation of a Virtual Reality Orientation and Mobility Test for Inherited Retinal Degenerations
por: Bennett, Jean, et al.
Publicado: (2023)

Effects of Different Spectrum of LEDs on Retinal Degeneration Through Regulating Endoplasmic Reticulum Stress
por: Chen, Wenyi, et al.
Publicado: (2023)

RBP–RNA interactions in the control of autoimmunity and autoinflammation
por: Liu, Juan, et al.
Publicado: (2023)

Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance
por: Moraes-Vieira, Pedro M., et al.
Publicado: (2016)

Involvement of RBP4 in all-trans retinoic acid induced cleft palate
por: Dong, Shiyi, et al.
Publicado: (2017)

RBP4 Is Associated With Insulin Resistance in Hyperuricemia-Induced Rats and Patients With Hyperuricemia
por: Liu, Chan, et al.
Publicado: (2021)

The Effect of RBP4 on microRNA Expression Profiles in Porcine Granulosa Cells
por: Zhao, Yun, et al.
Publicado: (2021)

Combined Transplantation With Human Mesenchymal Stem Cells Improves Retinal Rescue Effect of Human Fetal RPE Cells in Retinal Degeneration Mouse Model
por: Pan, Ting, et al.
Publicado: (2020)

Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome
por: Jabs, Douglas A., et al.
Publicado: (2018)

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
por: Narendran, Siddharth, et al.
Publicado: (2020)

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration
por: Gambril, J. Alan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k5khd3eeia3voiq07185ue5qbt