Cargando…

miR-133a Promotes TRAIL Resistance in Glioblastoma via Suppressing Death Receptor 5 and Activating NF-κB Signaling

Recombinant tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), as a novel cancer therapeutic, is being tested in phase II and III clinical trials; however, TRAIL resistance remains a big obstacle preventing its clinical application. Considering that TRAIL-induced apoptosis throug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shan-shan, Feng, Lu, Hu, Bao-guang, Lu, Ying-fei, Wang, Wei-mao, Guo, Wei, Suen, Chun-wai, Jiao, Bao-hua, Pang, Jian-xin, Fu, Wei-ming, Zhang, Jin-fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560119/ https://www.ncbi.nlm.nih.gov/pubmed/28918048 http://dx.doi.org/10.1016/j.omtn.2017.07.015

Ejemplares similares

Inhibition of NF-κB Pathway and Modulation of MAPK Signaling Pathways in Glioblastoma and Implications for Lovastatin and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) Combination Therapy
por: Liu, Pi Chu, et al.
Publicado: (2017)

A miR-137-XIAP axis contributes to the sensitivity of TRAIL-induced cell death in glioblastoma
por: Geng, Fenghao, et al.
Publicado: (2022)

MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway
por: Zheng, Zhen, et al.
Publicado: (2017)

NF-κB Signalling in Glioblastoma
por: Soubannier, Vincent, et al.
Publicado: (2017)

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway
por: Xiang, Jianyang, et al.
Publicado: (2022)

NF-κB, Mesenchymal Differentiation and Glioblastoma
por: Yamini, Bakhtiar
Publicado: (2018)

NF-κB-Regulated miR-99a Modulates Endothelial Cell Inflammation
por: Bao, Mei-hua, et al.
Publicado: (2016)

Targeting CD133 reverses drug-resistance via the AKT/NF-κB/MDR1 pathway in colorectal cancer
por: Yuan, Zeting, et al.
Publicado: (2020)

miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma
por: Zeng, Ailiang, et al.
Publicado: (2018)

miR-133a Regulates Adipocyte Browning In Vivo
por: Liu, Weiyi, et al.
Publicado: (2013)

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
por: Chan, David Y. L., et al.
Publicado: (2007)

Overcoming TRAIL Resistance for Glioblastoma Treatment
por: Deng, Longfei, et al.
Publicado: (2021)

The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL
por: Grunert, M, et al.
Publicado: (2012)

Parkin regulates NF-κB by mediating site-specific ubiquitination of RIPK1
por: Wang, Yu, et al.
Publicado: (2018)

NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma
por: Wang, Hui, et al.
Publicado: (2015)

BRD4 inhibition promotes TRAIL-induced apoptosis by suppressing the transcriptional activity of NF-κB in NSCLC
por: Shi, Liu, et al.
Publicado: (2021)

The Clinicopathological Significance of miR-133a in Colorectal Cancer
por: Wan, Timothy Ming-Hun, et al.
Publicado: (2014)

A MT1-MMP/NF-κB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cells
por: Annabi, Borhane, et al.
Publicado: (2009)

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma
por: Zhou, Jiahui, et al.
Publicado: (2016)

NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells
por: Han, Dongfeng, et al.
Publicado: (2015)

Upregulation of miR-335-3p by NF-κB Transcriptional Regulation Contributes to the Induction of Pulmonary Arterial Hypertension via APJ during Hypoxia
por: Fan, Junming, et al.
Publicado: (2020)

Long noncoding RNA00324 is involved in the inflammation of rheumatoid arthritis by targeting miR‐10a‐5p via the NF‐κB pathway
por: Xie, Binbin, et al.
Publicado: (2023)

Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells
por: Zhang, Hong-Mei, et al.
Publicado: (2017)

TRAIL/NF-κB/CX3CL1 Mediated Onco-Immuno Crosstalk Leading to TRAIL Resistance of Pancreatic Cancer Cell Lines
por: Geismann, Claudia, et al.
Publicado: (2018)

A CRTH2 antagonist, CT-133, suppresses NF-κB signalling to relieve lipopolysaccharide-induced acute lung injury
por: Hussain, Musaddique, et al.
Publicado: (2019)

Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-кB Pathway in Bladder Cancer Cells
por: Deng, Yuyou, et al.
Publicado: (2019)

The NFκB pathway: a therapeutic target in glioblastoma
por: Nogueira, Lorena, et al.
Publicado: (2011)

Targeting NF-κB in glioblastoma: A therapeutic approach
por: Friedmann-Morvinski, Dinorah, et al.
Publicado: (2016)

Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion
por: Feng, Feixue, et al.
Publicado: (2016)

Role of miR-1 and miR-133a in myocardial ischemic postconditioning
por: He, Bin, et al.
Publicado: (2011)

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death
por: Shan, Xiu, et al.
Publicado: (2015)

Ethyl pyruvate inhibits glioblastoma cells migration and invasion through modulation of NF-κB and ERK-mediated EMT
por: Huang, Qing, et al.
Publicado: (2020)

Id1 and NF-κB promote the generation of CD133(+) and BMI-1(+) keratinocytes and the growth of xenograft tumors in mice
por: LAI, JINHUO, et al.
Publicado: (2014)

Current approaches in enhancing TRAIL therapies in glioblastoma
por: Thang, Morrent, et al.
Publicado: (2023)

Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion
por: Wu, Zheng-sheng, et al.
Publicado: (2012)

Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF‐κB signalling participate in anti‐glioblastoma of imipramine
por: Hsu, Fei-Ting, et al.
Publicado: (2020)

Chronic Inflammation Pathway NF-κB Cooperates with Epigenetic Reprogramming to Drive the Malignant Progression of Glioblastoma
por: Lin, Kefeng, et al.
Publicado: (2022)

Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization
por: Cai, Jingjing, et al.
Publicado: (2014)

Targeting AGTR1/NF-κB/CXCR4 axis by miR-155 attenuates oncogenesis in glioblastoma
por: Singh, Anukriti, et al.
Publicado: (2020)

Following the fat trail to death
por: Williams, Ruth
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_p8u0fif5f2h7pdhi4dlroltffg