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The key role of microtubules in hypoxia preconditioning-induced nuclear translocation of HIF-1α in rat cardiomyocytes

BACKGROUND: Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and activates transcription of approximately 60 kinds...

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Detalles Bibliográficos
Autores principales:	Guo, Hai, Zheng, Hong, Wu, Jianjiang, Ma, Hai-ping, Yu, Jin, Yiliyaer, Maimaitili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560226/ https://www.ncbi.nlm.nih.gov/pubmed/28828258 http://dx.doi.org/10.7717/peerj.3662

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