Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T

[Image: see text] The human muscleblind-like proteins (MBNL) regulate tissue-specific splicing by targeting cardiac troponin T and other pre-mRNAs; aberrant targeting of CUG and CCUG repeat expansions frequently accompanies the neuromuscular disease myotonic dystrophy. We show, using biolayer interf...

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Detalles Bibliográficos
Autores principales: Park, Sangho, Phukan, Priti Deka, Zeeb, Markus, Martinez-Yamout, Maria A., Dyson, H. Jane, Wright, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560242/
https://www.ncbi.nlm.nih.gov/pubmed/28718627
http://dx.doi.org/10.1021/acs.biochem.7b00484

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