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Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations
INTRODUCTION: Vitamin B(3) has been shown to play an important role during embryogenesis. Specifically, there is growing evidence that nicotinamide, the biologically active form of vitamin B(3), plays a critical role as a morphogen in the differentiation of stem cells to mature cell phenotypes, incl...
Autores principales: | Griffin, Síle M., Pickard, Mark R., Orme, Rowan P., Hawkins, Clive P., Williams, Adrian C., Fricker, Rosemary A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560552/ https://www.ncbi.nlm.nih.gov/pubmed/28817722 http://dx.doi.org/10.1371/journal.pone.0183358 |
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