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Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B

BACKGROUND AND AIM: Caspase-cleaved cytokeratin 18 (CK18-Asp396) is a potential clinically useful biomarker in liver disease as it is released from hepatocytes during apoptosis. In this study, we investigated serum CK18-Asp396 levels in chronic hepatitis B (CHB). PATIENTS AND METHODS: Overall, 163 p...

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Detalles Bibliográficos
Autores principales: Li, Juan, Verhaar, Auke P, Pan, Qiuwei, de Knegt, Robert Jacobus, Peppelenbosch, Maikel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560566/
https://www.ncbi.nlm.nih.gov/pubmed/28860836
http://dx.doi.org/10.2147/CEG.S135526