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Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience

OBJECTIVES: Use of therapeutic flexible airway endoscopy (TFAE) is very limited in pediatrics. We report our clinical experiences and long term outcomes of TFAE in small children from a single tertiary referral center. METHODS: This is a retrospective cohort study. Small children with their body wei...

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Autores principales: Soong, Wen-Jue, Tsao, Pei-Chen, Lee, Yu-Sheng, Yang, Chia-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560590/
https://www.ncbi.nlm.nih.gov/pubmed/28817604
http://dx.doi.org/10.1371/journal.pone.0183078
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author Soong, Wen-Jue
Tsao, Pei-Chen
Lee, Yu-Sheng
Yang, Chia-Feng
author_facet Soong, Wen-Jue
Tsao, Pei-Chen
Lee, Yu-Sheng
Yang, Chia-Feng
author_sort Soong, Wen-Jue
collection PubMed
description OBJECTIVES: Use of therapeutic flexible airway endoscopy (TFAE) is very limited in pediatrics. We report our clinical experiences and long term outcomes of TFAE in small children from a single tertiary referral center. METHODS: This is a retrospective cohort study. Small children with their body weight no more than 5.0 kg who had received TFAE between 2005 and 2015 were enrolled. Demographic information and outcomes were reviewed and analyzed from medical charts and TFAE videos. RESULTS: A total of 313 TFAE were performed in 225 children. The mean age was 3.50 ± 0.24 (0.01–19.2) months old; the mean body weight was 3.52 ± 0.65 (0.57–5.0) kg. A noninvasive ventilation technique, without mask or artificial airway, was applied to support all the procedures. TFAE included laser therapy (39.6%), balloon dilatation plasty (25.6%), tracheal intubation (24.3%) and metallic stent placement (6.4%). Short-length endoscopes of 30–35 cm were used in 96%. All TFAE were successfully completed without serious adverse events or mortality. Mean procedural time was 27.6 ± 16.1 minutes. TFAE resulted in successful extubation immediately in 67.2% (45/67) and 62.8% (118/188) were able to wean off their positive pressure ventilation support in 7 days after procedures. By the end of this study, these TFAE averted the originally suggested airway surgeries in 93.8% (61/65), as benefited from laser therapy, stent implantation, and balloon dilatation plasty. CONCLUSIONS: The TFAE modality of using short-length endoscopes as supported with this noninvasive ventilation and ICU support is a viable, instant and effective management in small children. It has resulted in rapid weaning of respiratory supports and averted more invasive rigid endoscopy or airway surgeries.
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spelling pubmed-55605902017-08-25 Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience Soong, Wen-Jue Tsao, Pei-Chen Lee, Yu-Sheng Yang, Chia-Feng PLoS One Research Article OBJECTIVES: Use of therapeutic flexible airway endoscopy (TFAE) is very limited in pediatrics. We report our clinical experiences and long term outcomes of TFAE in small children from a single tertiary referral center. METHODS: This is a retrospective cohort study. Small children with their body weight no more than 5.0 kg who had received TFAE between 2005 and 2015 were enrolled. Demographic information and outcomes were reviewed and analyzed from medical charts and TFAE videos. RESULTS: A total of 313 TFAE were performed in 225 children. The mean age was 3.50 ± 0.24 (0.01–19.2) months old; the mean body weight was 3.52 ± 0.65 (0.57–5.0) kg. A noninvasive ventilation technique, without mask or artificial airway, was applied to support all the procedures. TFAE included laser therapy (39.6%), balloon dilatation plasty (25.6%), tracheal intubation (24.3%) and metallic stent placement (6.4%). Short-length endoscopes of 30–35 cm were used in 96%. All TFAE were successfully completed without serious adverse events or mortality. Mean procedural time was 27.6 ± 16.1 minutes. TFAE resulted in successful extubation immediately in 67.2% (45/67) and 62.8% (118/188) were able to wean off their positive pressure ventilation support in 7 days after procedures. By the end of this study, these TFAE averted the originally suggested airway surgeries in 93.8% (61/65), as benefited from laser therapy, stent implantation, and balloon dilatation plasty. CONCLUSIONS: The TFAE modality of using short-length endoscopes as supported with this noninvasive ventilation and ICU support is a viable, instant and effective management in small children. It has resulted in rapid weaning of respiratory supports and averted more invasive rigid endoscopy or airway surgeries. Public Library of Science 2017-08-17 /pmc/articles/PMC5560590/ /pubmed/28817604 http://dx.doi.org/10.1371/journal.pone.0183078 Text en © 2017 Soong et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Soong, Wen-Jue
Tsao, Pei-Chen
Lee, Yu-Sheng
Yang, Chia-Feng
Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title_full Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title_fullStr Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title_full_unstemmed Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title_short Therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
title_sort therapeutic flexible airway endoscopy of small children in a tertiary referral center—11 years’ experience
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560590/
https://www.ncbi.nlm.nih.gov/pubmed/28817604
http://dx.doi.org/10.1371/journal.pone.0183078
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