Cargando…

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma affecting children and is often diagnosed with concurrent metastases. Unfortunately, few effective therapies have been discovered that improve the long-term survival rate for children with metastatic disease. Here we determined effectiven...

Descripción completa

Detalles Bibliográficos
Autores principales:	Randolph, Matthew E., Cleary, Megan M., Bajwa, Zia, Svalina, Matthew N., Young, Michael C., Mansoor, Atiya, Kaur, Pali, Bult, Carol J., Goros, Martin W., Michalek, Joel E., Xiang, Sunny, Keck, James, Krasnoperov, Valery, Gill, Parkash, Keller, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560593/ https://www.ncbi.nlm.nih.gov/pubmed/28817624 http://dx.doi.org/10.1371/journal.pone.0183161

Ejemplares similares

EphB/ephrinB Signaling in Cell Adhesion and Migration
por: Park, Inji, et al.
Publicado: (2015)

EphrinB2–EphB4 Signaling in Neurooncological Disease
por: Piffko, Andras, et al.
Publicado: (2022)

Coexpression of EphB4 and ephrinB2 in tumour advancement of ovarian cancers
por: Alam, S M, et al.
Publicado: (2008)

A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
por: Thestrup, M. Ilcim, et al.
Publicado: (2019)

EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF
por: Groppa, Elena, et al.
Publicado: (2018)

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment
por: Bhatia, Shilpa, et al.
Publicado: (2022)

Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor
por: Xia, WS, et al.
Publicado: (2014)

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development
por: Li, Wenqing, et al.
Publicado: (2022)

EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment
por: Rohani, Nazanin, et al.
Publicado: (2011)

Effects of Porphyromonas gingivalis lipopolysaccharide on osteoblast-osteoclast bidirectional EphB4-EphrinB2 signaling
por: ZHANG, YI, et al.
Publicado: (2014)

Disturbed Expression of EphB4, but Not EphrinB2, Inhibited Bone Regeneration in an In Vivo Inflammatory Microenvironment
por: Shen, Li-Li, et al.
Publicado: (2016)

EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain-1 and caspase-3
por: Yang, Mei, et al.
Publicado: (2018)

Claudin 11 regulates bone homeostasis via bidirectional EphB4-EphrinB2 signaling
por: Baek, Jong Min, et al.
Publicado: (2018)

The coexpression of EphB4 and EphrinB2 is associated with poor prognosis in HER2-positive breast cancer
por: Li, Xuelu, et al.
Publicado: (2017)

EphB4/ephrinB2 Contributes to Imatinib Resistance in Chronic Myeloid Leukemia Involved in Cytoskeletal Proteins
por: Li, Lin, et al.
Publicado: (2016)

EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality
por: Cayuso, Jordi, et al.
Publicado: (2016)

The coexpression of EphB4 and EphrinB2 is associated with poor prognosis in HER2-positive breast cancer [Retraction]
Publicado: (2017)

Bidirectional ephrinB2-EphB4 signaling regulates the osteogenic differentiation of canine periodontal ligament stem cells
por: Zhu, Shaoyue, et al.
Publicado: (2020)

Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way
por: He, Chun-Hui, et al.
Publicado: (2023)

EphrinB3 blocks EphB3 dependence receptor functions to prevent cell death following traumatic brain injury
por: Theus, M H, et al.
Publicado: (2014)

Calcium channels are involved in EphB/ephrinB reverse signaling-induced apoptosis in a rat chronic ocular hypertension model
por: Dong, Lingdan, et al.
Publicado: (2018)

Modeling EphB4-EphrinB2 protein–protein interaction using flexible docking of a short linear motif
por: Ciemny, Maciej Pawel, et al.
Publicado: (2017)

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity
por: Frye, Maike, et al.
Publicado: (2020)

Loading of erythropoietin on biphasic calcium phosphate bioceramics promotes osteogenesis and angiogenesis by regulating EphB4/EphrinB2 molecules
por: Wang, Yu, et al.
Publicado: (2022)

PI3K Contributed to Modulation of Spinal Nociceptive Information Related to ephrinBs/EphBs
por: Yu, Li-Na, et al.
Publicado: (2012)

The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo
por: Ge, Yu-Wei, et al.
Publicado: (2020)

EphB4 as a therapeutic target in mesothelioma
por: Liu, Ren, et al.
Publicado: (2013)

Compressive force regulates ephrinB2 and EphB4 in osteoblasts and osteoclasts contributing to alveolar bone resorption during experimental tooth movement
por: Hou, Jianhua, et al.
Publicado: (2014)

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis
por: Djokovic, Dusan, et al.
Publicado: (2010)

High expression of erythropoietin-producing hepatoma cell line-B2 (EphB2) predicts the efficiency of the Qingyihuaji formula treatment in pancreatic cancer CFPAC-1 cells through the EphrinB1-EphB2 pathway
por: HUA, YONG-QIANG, et al.
Publicado: (2014)

Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose-induced osteoblast dysfunction and hyperglycemia-induced bone deterioration in mice
por: WU, MIN, et al.
Publicado: (2016)

Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose‑induced osteoblast dysfunction and hyperglycemia‑induced bone deterioration in mice
por: Wu, Min, et al.
Publicado: (2019)

Low-intensity pulsed ultrasound regulates osteoblast-osteoclast crosstalk via EphrinB2/EphB4 signaling for orthodontic alveolar bone remodeling
por: Zhou, Jie, et al.
Publicado: (2023)

The Differential Expression of EphB2 and EphB4 Receptor Kinases in Normal Bladder and in Transitional Cell Carcinoma of the Bladder
por: Li, Xiuqing, et al.
Publicado: (2014)

Critical roles for EphB and ephrin-B bidirectional signaling in retinocollicular mapping
por: Thakar, Sonal, et al.
Publicado: (2011)

Peripheral EphrinB1/EphB1 signalling attenuates muscle hyperalgesia in MPS patients and a rat model of taut band-associated persistent muscle pain
por: Jin, Feihong, et al.
Publicado: (2020)

The ephrin receptor EphB2 regulates the connectivity and activity of enteric neurons
por: Bodin, Raphael, et al.
Publicado: (2021)

EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model
por: Liu, Shu-Ting, et al.
Publicado: (2018)

Dysregulation of the EphrinB2−EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients
por: Fehnel, Katie Pricola, et al.
Publicado: (2020)

EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands
por: Vreeken, Dianne, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rpo24t0ivopeqrqte66krgas77