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The transcriptional profiling of human in vivo-generated plasma cells identifies selective imbalances in monoclonal gammopathies

Plasma cells (PC) represent the heterogeneous final stage of the B cells (BC) differentiation process. To characterize the transition of BC into PC, transcriptomes from human naïve BC were compared to those of three functionally-different subsets of human in vivo-generated PC: i) tonsil PC, mainly c...

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Detalles Bibliográficos
Autores principales: Valor, Luis M., Rodríguez-Bayona, Beatriz, Ramos-Amaya, Ana B., Brieva, José A., Campos-Caro, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560601/
https://www.ncbi.nlm.nih.gov/pubmed/28817638
http://dx.doi.org/10.1371/journal.pone.0183264