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Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in Echinococcus granulosus larval stage

Cystic echinococcosis (CE) is a worldwide distributed helminthic zoonosis caused by Echinococcus granulosus. Benzimidazole derivatives are currently the only drugs for chemotherapeutic treatment of CE. However, their low efficacy and the adverse effects encourage the search for new therapeutic targe...

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Detalles Bibliográficos
Autores principales: Nicolao, María Celeste, Loos, Julia A., Rodriguez Rodrigues, Christian, Beas, Viviana, Cumino, Andrea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560652/
https://www.ncbi.nlm.nih.gov/pubmed/28817601
http://dx.doi.org/10.1371/journal.pone.0181528