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The brain-penetrant 5-HT(7) receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

Neuropathic pain is a debilitating pathological condition of high clinical relevance. Changes in neuronal excitability in the anterior cingulate cortex (ACC) play a central role in the negative emotional and affective aspects of chronic pain. We evaluated the effects of LP-211, a new serotonin-recep...

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Detalles Bibliográficos
Autores principales:	Santello, Mirko, Bisco, Alberto, Nevian, Natalie Elisabeth, Lacivita, Enza, Leopoldo, Marcello, Nevian, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560654/ https://www.ncbi.nlm.nih.gov/pubmed/28690143 http://dx.doi.org/10.1016/j.nbd.2017.07.005

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