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Alzheimer's brains show inter-related changes in RNA and lipid metabolism

Alzheimer's disease (AD) involves changes in both lipid and RNA metabolism, but it remained unknown if these differences associate with AD's cognition and/or post-mortem neuropathology indices. Here, we report RNA-sequencing evidence of inter-related associations between lipid processing,...

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Detalles Bibliográficos
Autores principales: Barbash, Shahar, Garfinkel, Benjamin P., Maoz, Rotem, Simchovitz, Alon, Nadorp, Bettina, Guffanti, Alessandro, Bennett, Estelle R., Nadeau, Courtney, Türk, Andreas, Paul, Lukas, Reda, Torsten, Li, Yan, Buchman, Aron S., Greenberg, David S., Seitz, Alexander, Bennett, David A., Giavalisco, Patrick, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560656/
https://www.ncbi.nlm.nih.gov/pubmed/28630030
http://dx.doi.org/10.1016/j.nbd.2017.06.008

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