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Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner

Mechano-transduction is an emerging but still poorly understood component of T cell activation. Here we investigated the ligand-dependent contribution made by contractile actomyosin arcs populating the peripheral supramolecular activation cluster (pSMAC) region of the immunological synapse (IS) to T...

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Detalles Bibliográficos
Autores principales: Hong, Jinsung, Murugesan, Sricharan, Betzig, Eric, Hammer, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560663/
https://www.ncbi.nlm.nih.gov/pubmed/28817635
http://dx.doi.org/10.1371/journal.pone.0183174