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Evaluation of peptide designing strategy against subunit reassociation in mucin 1: A steered molecular dynamics approach
Subunit reassociation in mucin 1, a breast cancer tumor marker, is reported as one of the critical factors for its cytoplasmic activation. Inhibition of its heterodimeric association would therefore result in loss of its function and alter disease progression. The present study aimed at evaluating p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560680/ https://www.ncbi.nlm.nih.gov/pubmed/28817726 http://dx.doi.org/10.1371/journal.pone.0183041 |