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A parapoxviral virion protein inhibits NF-κB signaling early in infection

Poxviruses have evolved unique proteins and mechanisms to counteract the nuclear factor κB (NF-κB) signaling pathway, which is an essential regulatory pathway of host innate immune responses. Here, we describe a NF-κB inhibitory virion protein of orf virus (ORFV), ORFV073, which functions very early...

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Detalles Bibliográficos
Autores principales: Khatiwada, Sushil, Delhon, Gustavo, Nagendraprabhu, Ponnuraj, Chaulagain, Sabal, Luo, Shuhong, Diel, Diego G., Flores, Eduardo F., Rock, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560748/
https://www.ncbi.nlm.nih.gov/pubmed/28787456
http://dx.doi.org/10.1371/journal.ppat.1006561