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cAMP-dependent regulation of I(Ks) single-channel kinetics

The delayed potassium rectifier current, I(Ks), is composed of KCNQ1 and KCNE1 subunits and plays an important role in cardiac action potential repolarization. During β-adrenergic stimulation, 3′-5′-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) phosphorylates KCNQ1, producin...

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Detalles Bibliográficos
Autores principales:	Thompson, Emely, Eldstrom, Jodene, Westhoff, Maartje, McAfee, Donald, Balse, Elise, Fedida, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560775/ https://www.ncbi.nlm.nih.gov/pubmed/28687606 http://dx.doi.org/10.1085/jgp.201611734

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