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Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3

Dynamic remodelling of the extracellular matrix (ECM) is a key feature of cancer progression. Enzymes that modify the ECM, such as matrix metalloproteinases (MMPs), have long been recognised as important targets of anticancer therapy. Inflammatory cytokines are known to play a key role in regulating...

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Detalles Bibliográficos
Autores principales:	Cutler, Samuel J., Doecke, James D., Ghazawi, Ibtisam, Yang, Jinbo, Griffiths, Lyn R., Spring, Kevin J., Ralph, Stephen J., Mellick, Albert S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561029/ https://www.ncbi.nlm.nih.gov/pubmed/28819304 http://dx.doi.org/10.1038/s41598-017-08581-y

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