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Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease

PGC-1α is a versatile inducer of mitochondrial biogenesis and responsive to the changing energy demands of the cell. As mitochondrial ATP production requires proteins that derive from translation products of cytosolic ribosomes, we asked whether PGC-1α directly takes part in ribosomal biogenesis. He...

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Detalles Bibliográficos
Autores principales:	Jesse, Sarah, Bayer, Hanna, Alupei, Marius C., Zügel, Martina, Mulaw, Medhanie, Tuorto, Francesca, Malmsheimer, Silke, Singh, Karmveer, Steinacker, Jürgen, Schumann, Uwe, Ludolph, Albert C., Scharffetter-Kochanek, Karin, Witting, Anke, Weydt, Patrick, Iben, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561056/ https://www.ncbi.nlm.nih.gov/pubmed/28819135 http://dx.doi.org/10.1038/s41598-017-09148-7

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