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Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones
Eusocial insects use cuticular hydrocarbons as components of pheromones that mediate social behaviours, such as caste and nestmate recognition, and regulation of reproduction. In ants such as Harpegnathos saltator, the queen produces a pheromone which suppresses the development of workers’ ovaries a...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561057/ https://www.ncbi.nlm.nih.gov/pubmed/28819196 http://dx.doi.org/10.1038/s41467-017-00099-1 |
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author | Pask, Gregory M. Slone, Jesse D. Millar, Jocelyn G. Das, Prithwiraj Moreira, Jardel A. Zhou, Xiaofan Bello, Jan Berger, Shelley L. Bonasio, Roberto Desplan, Claude Reinberg, Danny Liebig, Jürgen Zwiebel, Laurence J. Ray, Anandasankar |
author_facet | Pask, Gregory M. Slone, Jesse D. Millar, Jocelyn G. Das, Prithwiraj Moreira, Jardel A. Zhou, Xiaofan Bello, Jan Berger, Shelley L. Bonasio, Roberto Desplan, Claude Reinberg, Danny Liebig, Jürgen Zwiebel, Laurence J. Ray, Anandasankar |
author_sort | Pask, Gregory M. |
collection | PubMed |
description | Eusocial insects use cuticular hydrocarbons as components of pheromones that mediate social behaviours, such as caste and nestmate recognition, and regulation of reproduction. In ants such as Harpegnathos saltator, the queen produces a pheromone which suppresses the development of workers’ ovaries and if she is removed, workers can transition to a reproductive state known as gamergate. Here we functionally characterize a subfamily of odorant receptors (Ors) with a nine-exon gene structure that have undergone a massive expansion in ants and other eusocial insects. We deorphanize 22 representative members and find they can detect cuticular hydrocarbons from different ant castes, with one (HsOr263) that responds strongly to gamergate extract and a candidate queen pheromone component. After systematic testing with a diverse panel of hydrocarbons, we find that most Harpegnathos saltator Ors are narrowly tuned, suggesting that several receptors must contribute to detection and discrimination of different cuticular hydrocarbons important in mediating eusocial behaviour. |
format | Online Article Text |
id | pubmed-5561057 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55610572017-08-28 Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones Pask, Gregory M. Slone, Jesse D. Millar, Jocelyn G. Das, Prithwiraj Moreira, Jardel A. Zhou, Xiaofan Bello, Jan Berger, Shelley L. Bonasio, Roberto Desplan, Claude Reinberg, Danny Liebig, Jürgen Zwiebel, Laurence J. Ray, Anandasankar Nat Commun Article Eusocial insects use cuticular hydrocarbons as components of pheromones that mediate social behaviours, such as caste and nestmate recognition, and regulation of reproduction. In ants such as Harpegnathos saltator, the queen produces a pheromone which suppresses the development of workers’ ovaries and if she is removed, workers can transition to a reproductive state known as gamergate. Here we functionally characterize a subfamily of odorant receptors (Ors) with a nine-exon gene structure that have undergone a massive expansion in ants and other eusocial insects. We deorphanize 22 representative members and find they can detect cuticular hydrocarbons from different ant castes, with one (HsOr263) that responds strongly to gamergate extract and a candidate queen pheromone component. After systematic testing with a diverse panel of hydrocarbons, we find that most Harpegnathos saltator Ors are narrowly tuned, suggesting that several receptors must contribute to detection and discrimination of different cuticular hydrocarbons important in mediating eusocial behaviour. Nature Publishing Group UK 2017-08-17 /pmc/articles/PMC5561057/ /pubmed/28819196 http://dx.doi.org/10.1038/s41467-017-00099-1 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Pask, Gregory M. Slone, Jesse D. Millar, Jocelyn G. Das, Prithwiraj Moreira, Jardel A. Zhou, Xiaofan Bello, Jan Berger, Shelley L. Bonasio, Roberto Desplan, Claude Reinberg, Danny Liebig, Jürgen Zwiebel, Laurence J. Ray, Anandasankar Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title | Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title_full | Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title_fullStr | Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title_full_unstemmed | Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title_short | Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
title_sort | specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561057/ https://www.ncbi.nlm.nih.gov/pubmed/28819196 http://dx.doi.org/10.1038/s41467-017-00099-1 |
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