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Multiple E3s promote the degradation of histone H3 variant Cse4

The histone H3-like protein Cse4/CENP-A acts as a key molecular marker that differentiates the special centromeric chromatin structures from bulk nucleosomes. As altered Cse4/CENP-A activity leads to genome instability, it is pivotal to understand the mechanism underlying Cse4 regulation. Here, we d...

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Detalles Bibliográficos
Autores principales: Cheng, Haili, Bao, Xin, Gan, Xin, Luo, Shiwen, Rao, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561092/
https://www.ncbi.nlm.nih.gov/pubmed/28819127
http://dx.doi.org/10.1038/s41598-017-08923-w

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