Blockage of the lysosome-dependent autophagic pathway contributes to complement membrane attack complex-induced podocyte injury in idiopathic membranous nephropathy

Dysregulation of autophagy-mediated podocyte homeostasis is proposed to play a role in idiopathic membranous nephropathy (IMN). In the present study, autophagic activity and lysosomal alterations were investigated in podocytes of IMN patients and in cultured podocytes exposed to sublytic terminal co...

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Detalles Bibliográficos
Autores principales: Liu, Wei Jing, Li, Zhi-hang, Chen, Xiao-cui, Zhao, Xiao-lu, Zhong, Zhen, Yang, Chen, Wu, Hong-luan, An, Ning, Li, Wei-yan, Liu, Hua-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561110/
https://www.ncbi.nlm.nih.gov/pubmed/28819100
http://dx.doi.org/10.1038/s41598-017-07889-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561110/
https://www.ncbi.nlm.nih.gov/pubmed/28819100
http://dx.doi.org/10.1038/s41598-017-07889-z

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