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Hypoxia triggers IFN-I production in muscle: Implications in dermatomyositis

Dermatomyositis is an inflammatory myopathy characterized by symmetrical proximal muscle weakness and skin changes. Muscle biopsy hallmarks include perifascicular atrophy, loss of intramuscular capillaries, perivascular and perimysial inflammation and the overexpression of IFN-inducible genes. Among...

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Detalles Bibliográficos
Autores principales: De Luna, Noemí, Suárez-Calvet, Xavier, Lleixà, Cinta, Diaz-Manera, Jordi, Olivé, Montse, Illa, Isabel, Gallardo, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561123/
https://www.ncbi.nlm.nih.gov/pubmed/28819164
http://dx.doi.org/10.1038/s41598-017-09309-8