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Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells

PURPOSE: To observe the nuclear expression and interaction of heparanase and RNA polymerase II (RNA Pol II), an enzyme that catalyzes the transcription of DNA in eukaryotic cells) in human retinal microvascular endothelial cells (HRECs) under high glucose condition and to investigate the association...

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Detalles Bibliográficos
Autores principales: Hu, Jie, Wang, Jingwei, Leng, Xuan, Hu, Yijun, Shen, Huangxuan, Song, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561135/
https://www.ncbi.nlm.nih.gov/pubmed/28848320