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Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model

Pluripotent stem cell-derived cardiomyocytes show great promise in regenerating the heart after myocardial infarction; however, several uncertainties exist that must be addressed before clinical trials. One practical issue is graft survival following transplantation. Although a pro-survival cocktail...

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Detalles Bibliográficos
Autores principales: Ogasawara, Tatsuki, Okano, Satomi, Ichimura, Hajime, Kadota, Shin, Tanaka, Yuki, Minami, Itsunari, Uesugi, Motonari, Wada, Yuko, Saito, Naoto, Okada, Kenji, Kuwahara, Koichiro, Shiba, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561148/
https://www.ncbi.nlm.nih.gov/pubmed/28819182
http://dx.doi.org/10.1038/s41598-017-09217-x