HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy

Cardiovascular disease is a leading cause of co-morbidity in HIV-1 positive patients, even those in whom plasma virus levels are well-controlled. The pathogenic mechanism of HIV-1-associated cardiomyopathy is unknown, but has been presumed to be mediated indirectly, owing to the absence of productiv...

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Detalles Bibliográficos
Autores principales: Gupta, Manish K., Kaminski, Rafal, Mullen, Brian, Gordon, Jennifer, Burdo, Tricia H., Cheung, Joseph Y., Feldman, Arthur M., Madesh, Muniswamy, Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561171/
https://www.ncbi.nlm.nih.gov/pubmed/28819214
http://dx.doi.org/10.1038/s41598-017-08736-x

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