Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents

Among the enzymes involved in the post-translational modification of Ras, isoprenyl carboxyl methyltransferase (ICMT) has been explored by a number of researchers as a significant enzyme controlling the activation of Ras. Indeed, inhibition of ICMT exhibited promising anti-cancer activity against va...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Woo Seok, Yeo, Seung-Gu, Yang, Sungjae, Kim, Kyung-Hee, Yoo, Byong Chul, Cho, Jae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561173/
https://www.ncbi.nlm.nih.gov/pubmed/28631011
http://dx.doi.org/10.1007/s00726-017-2454-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561173/
https://www.ncbi.nlm.nih.gov/pubmed/28631011
http://dx.doi.org/10.1007/s00726-017-2454-x

Ejemplares similares