Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems

Metformin is an antidiabetic drug, which inhibits mitochondrial respiratory-chain-complex I and thereby seems to affect the cellular metabolism in many ways. It is also used for the treatment of the polycystic ovary syndrome (PCOS), the most common endocrine disorder in women. In addition, metformin...

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Detalles Bibliográficos
Autores principales: Udhane, Sameer S., Legeza, Balazs, Marti, Nesa, Hertig, Damian, Diserens, Gaëlle, Nuoffer, Jean-Marc, Vermathen, Peter, Flück, Christa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561186/
https://www.ncbi.nlm.nih.gov/pubmed/28819133
http://dx.doi.org/10.1038/s41598-017-09189-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561186/
https://www.ncbi.nlm.nih.gov/pubmed/28819133
http://dx.doi.org/10.1038/s41598-017-09189-y

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