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Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems
Metformin is an antidiabetic drug, which inhibits mitochondrial respiratory-chain-complex I and thereby seems to affect the cellular metabolism in many ways. It is also used for the treatment of the polycystic ovary syndrome (PCOS), the most common endocrine disorder in women. In addition, metformin...
Autores principales: | Udhane, Sameer S., Legeza, Balazs, Marti, Nesa, Hertig, Damian, Diserens, Gaëlle, Nuoffer, Jean-Marc, Vermathen, Peter, Flück, Christa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561186/ https://www.ncbi.nlm.nih.gov/pubmed/28819133 http://dx.doi.org/10.1038/s41598-017-09189-y |
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