Mouse strain differences in SSRI sensitivity correlate with serotonin transporter binding and function

Selective serotonin reuptake inhibitors (SSRIs) bind 5-HT transporters, leading to the accumulation of 5-HT and amelioration of depression. Although different mouse strains show varying sensitivity to SSRIs in mouse models of depression, the underlying mechanism of these strain differences remains u...

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Detalles Bibliográficos
Autores principales: Jin, Zeng-liang, Chen, Xiao-Fei, Ran, Yu-hua, Li, Xiao-rong, Xiong, Jie, Zheng, Yuan-yuan, Gao, Na-na, Li, Yun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561191/
https://www.ncbi.nlm.nih.gov/pubmed/28819255
http://dx.doi.org/10.1038/s41598-017-08953-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561191/
https://www.ncbi.nlm.nih.gov/pubmed/28819255
http://dx.doi.org/10.1038/s41598-017-08953-4

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