Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo

Modified Vaccinia virus Ankara (MVA) is a promising vaccine vector with an excellent safety profile. However, despite extensive pre-clinical and clinical testing, surprisingly little is known about the cellular tropism of MVA, especially in relevant animal species. Here, we performed in vitro, ex vi...

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Detalles Bibliográficos
Autores principales: Altenburg, Arwen F., van de Sandt, Carolien E., Li, Bobby W. S., MacLoughlin, Ronan J., Fouchier, Ron A. M., van Amerongen, Geert, Volz, Asisa, Hendriks, Rudi W., de Swart, Rik L., Sutter, Gerd, Rimmelzwaan, Guus F., de Vries, Rory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561217/
https://www.ncbi.nlm.nih.gov/pubmed/28819261
http://dx.doi.org/10.1038/s41598-017-08719-y

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