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14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency
BACKGROUND: Inducible co-stimulator (ICOS) deficiency was the first monogenic defect reported to cause common variable immunodeficiency (CVID)-like disease in 2003. Since then, 16 patients have been reported worldwide with an increasing range of clinical phenotypes. OBJECTIVE: We sought to compare t...
Autores principales: | Schepp, Johanna, Chou, Janet, Skrabl-Baumgartner, Andrea, Arkwright, Peter D., Engelhardt, Karin R., Hambleton, Sophie, Morio, Tomohiro, Röther, Ekkehard, Warnatz, Klaus, Geha, Raif, Grimbacher, Bodo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561331/ https://www.ncbi.nlm.nih.gov/pubmed/28861081 http://dx.doi.org/10.3389/fimmu.2017.00964 |
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