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Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up
OBJECTIVE: Antifibrillar collagen type II (anti-CII) antibody-positive patients with rheumatoid arthritis (RA) have early but not late signs of increased inflammation and joint erosions. We wanted to replicate this in a large RA cohort, and to relate to human leukocyte antigen (HLA)-DRB1* alleles. M...
Autores principales: | Manivel, Vivek Anand, Mullazehi, Mohammed, Padyukov, Leonid, Westerlind, Helga, Klareskog, Lars, Alfredsson, Lars, Saevarsdottir, Saedis, Rönnelid, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561381/ https://www.ncbi.nlm.nih.gov/pubmed/28336519 http://dx.doi.org/10.1136/annrheumdis-2016-210873 |
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