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Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines
OBJECTIVE: Mind-body training (MBT) may control reactions to stress and regulate the nervous and immune systems. The present study was designed to assess the effects of MBT on plasma cytokines and their interactions with catecholamines. METHODS: The study group consisted of 80 subjects who practice...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Neuropsychiatric Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561407/ https://www.ncbi.nlm.nih.gov/pubmed/28845176 http://dx.doi.org/10.4306/pi.2017.14.4.483 |
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author | Jang, Joon Hwan Park, Hye Yoon Lee, UI Soon Lee, Kyung-Jun Kang, Do-Hyung |
author_facet | Jang, Joon Hwan Park, Hye Yoon Lee, UI Soon Lee, Kyung-Jun Kang, Do-Hyung |
author_sort | Jang, Joon Hwan |
collection | PubMed |
description | OBJECTIVE: Mind-body training (MBT) may control reactions to stress and regulate the nervous and immune systems. The present study was designed to assess the effects of MBT on plasma cytokines and their interactions with catecholamines. METHODS: The study group consisted of 80 subjects who practice MBT and a control group of 62 healthy subjects. Plasma catecholamine (norepinephrine, NE; epinephrine, E; and dopamine, DA) and cytokine (TNF-alpha, IL-6, IFN-gamma, and IL-10) levels were measured, and the differences between the MBT and control groups and the interactions of cytokines with catecholamines were investigated. RESULTS: A significant increase in IL-10+IFN-gamma was found in females of the MBT group compared with controls. Also, a significant increase of IL-10 (anti-inflammatory cytokine) in the MBT group was shown in a specific condition in which TNF-alpha and IL-6 (pro-inflammatory cytokines) are almost absent (≤1 ng/L) compared with controls. In the MBT group, significant positive correlations were found between IL-10 and the NE/E ratio and between IL-10 and the DA/E ratio, whereas the control group did not show any such correlations. CONCLUSION: MBT may increase IL-10, under specific conditions such as a decrease of pro-inflammatory cytokines or E, which may regulate the stress response and possibly contribute to effective and beneficial interactions between the nervous and immune systems. |
format | Online Article Text |
id | pubmed-5561407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Korean Neuropsychiatric Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-55614072017-08-25 Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines Jang, Joon Hwan Park, Hye Yoon Lee, UI Soon Lee, Kyung-Jun Kang, Do-Hyung Psychiatry Investig Original Article OBJECTIVE: Mind-body training (MBT) may control reactions to stress and regulate the nervous and immune systems. The present study was designed to assess the effects of MBT on plasma cytokines and their interactions with catecholamines. METHODS: The study group consisted of 80 subjects who practice MBT and a control group of 62 healthy subjects. Plasma catecholamine (norepinephrine, NE; epinephrine, E; and dopamine, DA) and cytokine (TNF-alpha, IL-6, IFN-gamma, and IL-10) levels were measured, and the differences between the MBT and control groups and the interactions of cytokines with catecholamines were investigated. RESULTS: A significant increase in IL-10+IFN-gamma was found in females of the MBT group compared with controls. Also, a significant increase of IL-10 (anti-inflammatory cytokine) in the MBT group was shown in a specific condition in which TNF-alpha and IL-6 (pro-inflammatory cytokines) are almost absent (≤1 ng/L) compared with controls. In the MBT group, significant positive correlations were found between IL-10 and the NE/E ratio and between IL-10 and the DA/E ratio, whereas the control group did not show any such correlations. CONCLUSION: MBT may increase IL-10, under specific conditions such as a decrease of pro-inflammatory cytokines or E, which may regulate the stress response and possibly contribute to effective and beneficial interactions between the nervous and immune systems. Korean Neuropsychiatric Association 2017-07 2017-07-11 /pmc/articles/PMC5561407/ /pubmed/28845176 http://dx.doi.org/10.4306/pi.2017.14.4.483 Text en Copyright © 2017 Korean Neuropsychiatric Association http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jang, Joon Hwan Park, Hye Yoon Lee, UI Soon Lee, Kyung-Jun Kang, Do-Hyung Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title | Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title_full | Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title_fullStr | Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title_full_unstemmed | Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title_short | Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines |
title_sort | effects of mind-body training on cytokines and their interactions with catecholamines |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561407/ https://www.ncbi.nlm.nih.gov/pubmed/28845176 http://dx.doi.org/10.4306/pi.2017.14.4.483 |
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