Cargando…

Contrasting Phenotypes in Resistance to Thyroid Hormone Alpha Correlate with Divergent Properties of Thyroid Hormone Receptor α1 Mutant Proteins

Background: Resistance to thyroid hormone alpha (RTHα), a disorder characterized by tissue-selective hypothyroidism and near-normal thyroid function tests due to thyroid receptor alpha gene mutations, is rare but probably under-recognized. This study sought to correlate the clinical characteristics...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moran, Carla, Agostini, Maura, McGowan, Anne, Schoenmakers, Erik, Fairall, Louise, Lyons, Greta, Rajanayagam, Odelia, Watson, Laura, Offiah, Amaka, Barton, John, Price, Susan, Schwabe, John, Chatterjee, Krishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2017
Materias:	Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561448/ https://www.ncbi.nlm.nih.gov/pubmed/28471274 http://dx.doi.org/10.1089/thy.2017.0157

Ejemplares similares

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi
por: Di Cicco, Emery, et al.
Publicado: (2021)

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha
por: Freudenthal, Bernard, et al.
Publicado: (2019)

Thyroid Hormone Transporters in a Human Placental Cell Model
por: Chen, Zhongli, et al.
Publicado: (2022)

Thyroid hormones regulate both cardiovascular and renal mechanisms underlying hypertension
por: Jankauskas, Stanislovas S., et al.
Publicado: (2020)

Association of thyroid hormones with blood pressure and arterial stiffness in the general population: The Dali study
por: Jamal, Md Tasneem, et al.
Publicado: (2020)

Altered Intracellular Trafficking of Mutant Thyroid Hormone Receptors in Resistance to Thyroid Hormone Syndrome
por: Tofil, Hannah P, et al.
Publicado: (2021)

Thyroid Hormone Resistance With Concurrent Papillary Thyroid Cancer
por: Pahwa, Dhivya, et al.
Publicado: (2021)

FRI479 Resistance To Thyroid Hormone Due To Thyroid Hormone Receptor Alpha (THRA) Gene Mutation
por: Omar Abdelkarim, Jumana, et al.
Publicado: (2023)

Transcriptome Network Analysis Reveals Aging-Related Mitochondrial and Proteasomal Dysfunction and Immune Activation in Human Thyroid
por: Cho, Byuri Angela, et al.
Publicado: (2018)

SUN-546 Coexistent Resistance to Thyroid Hormone Beta and Viral Thyroiditis
por: Golubic, Rajna, et al.
Publicado: (2019)

OR26-06 Cardiovascular Morbidity And Mortality In Patients With Resistance to THYROID Hormone (RTH): A Linked Record Study
por: Okosieme, Onyebuchi, et al.
Publicado: (2023)

ODP521 THYROID HORMONE RESISTANCE SYNDROME
por: Franco, Katty Manrique, et al.
Publicado: (2022)

Coexistence of Thyroid Hormone Resistance and Autoimmune Thyroid Disease: Not a Mere Coincidence
por: Gnanapragasam, Helen Prathiba, et al.
Publicado: (2021)

Effectiveness of Different Thyroid Stimulating Hormone Thresholds for Thyroid Hormone Withdrawal - Aided Radioiodine Ablation in Patients With Differentiated Thyroid Cancer: A Systematic Review and Meta - Analysis
por: Rojas, Tatiana, et al.
Publicado: (2021)

SAT504 Thyroidal Pax de Deux: 2 Cases of Resistance to Thyroid Hormone and Coexisting Thyroid Disease
por: Ribeiro, Sara V, et al.
Publicado: (2023)

SAT-426 Macro-Thyroid Stimulating Hormone (TSH) in Children
por: Hattori, Naoki, et al.
Publicado: (2020)

Hyperthyroidism Times 2: Dual Cause of Thyroid Hormone Excess
por: Ortiz, Yineli, et al.
Publicado: (2021)

Analysis of Hypothalamic TRH Neurons in Regulating Thyroid Hormone Levels
por: Costa e Sousa, Ricardo H, et al.
Publicado: (2021)

SAT-562 Thyroid Hormone Transporter Mct8 is Specially Expressed in the Adrenal Gland Inner Cortex and Partially Mediates the Thyroid Hormone Action in the Adrenal Cortex.
por: Cleary, Courtney, et al.
Publicado: (2019)

OR10-5 Reduced Sensitivity to Thyroid Hormone Due to Fetal Exposure to High Thyroid Hormone Levels Is Transmitted along Male Line to Two Subsequent Generations
por: Anselmo, Joao, et al.
Publicado: (2019)

SAT-571 Restoration of Thyroid Hormone Receptor Beta Signaling Reprograms Anaplastic Thyroid Cancer Cells
por: Gillis, Noelle, et al.
Publicado: (2019)

MON-472 A Case of Resistance to Thyroid Hormone with Concurrent Hashimoto’s Thyroiditis and Post-Surgical Hypothyroidism
por: Bernthal, Julie, et al.
Publicado: (2020)

ODP528 Unwrapping The Mystery in a Hormonal Sandwich - Intra-thyroid Parathyroid with Thyroid Papillary Microcarcinoma
por: Arora, Gunjan, et al.
Publicado: (2022)

FRI488 The Effect Of Thyroid Stimulating Hormone On Brown Adipose Tissue In Humans
por: Salej, Laura, et al.
Publicado: (2023)

SAT-573 Characterization of the Gene Expression Program of a Mutant Thyroid Hormone Receptor in Anaplastic Thyroid Cancer
por: Bolf, Eric, et al.
Publicado: (2019)

OR14-03 The Thyroid Hormone Receptor Beta Genotype Of The Fetus Influences The Maternal Thyroid Function During Pregnancy
por: Salas Lucia, Federico, et al.
Publicado: (2023)

SAT-LB094 The Role of Thyroid Hormone in the Beneficial Effects of Stretching
por: Carmody, Colleen, et al.
Publicado: (2019)

SUN-LB097 Thyroid Hormone Resistance Simulating Graves Disease
por: Ballestas-Revollo, Martha, et al.
Publicado: (2019)

Interfering Medications in Older Adults on Thyroid Hormone Replacement: Who Is at Risk?
por: Beeson, Rachel, et al.
Publicado: (2021)

Transcriptional and Genomic Regulation of Pituitary Function by Thyroid Hormone Receptor Beta
por: Cho, Young-Wook, et al.
Publicado: (2021)

High-Dose Thyroid Hormone Replacement in Bexarotene-Induced Central Hypothyroidism
por: Mathews, Tony, et al.
Publicado: (2021)

Antiepileptic Drugs and Thyroid Hormone Homeostasis: Literature Review and Practical Guideline
por: Rochtus, Anne Maria, et al.
Publicado: (2021)

FRI496 A Rare Case Of Thyroid Hormone Resistance Beta
por: Kaur Rai, Harpreet, et al.
Publicado: (2023)

SAT510 I-131 Therapy with Dosimetry for Advanced Thyroid Carcinoma: Recombinant TSH vs Thyroid Hormone Withdrawal
por: Awad, Dana, et al.
Publicado: (2023)

MON-LB101 Pharmacokinetics of Liothyronine during Thyroid Hormone Therapy Withdrawal
por: Celi, Francesco, et al.
Publicado: (2019)

OR10-1 Regulation of Glucocorticoid Metabolism: A Novel Function for Thyroid Hormones?
por: Bessiene, Laura, et al.
Publicado: (2019)

SAT-559 Intranuclear Dynamics of RTHα Mutant Thyroid Hormone Receptors
por: Evans, Rochelle, et al.
Publicado: (2019)

SAT-551 Thyroid Hormone Effects on the Methylome During Post-Embryonic Development
por: Jonchere, Vincent, et al.
Publicado: (2019)

MON-478 Impaired Sensitivity to Thyroid Hormone - A Diagnostic and Therapeutic Challenge
por: Pedro, Jorge, et al.
Publicado: (2020)

FRI526 Geographic Trends In Thyroid Hormone Prescribing In The US: 2010 - 2020
por: Ettleson, Matthew D, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g285hogb0na4vmprjgas9ubiea