Cargando…

Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study

BACKGROUND: Higher levels of frailty result in higher risks of adverse frailty outcomes such as hospitalisation and mortality. There are, however, indications that more factors than solely frailty play a role in the development of these outcomes. The presence of resources, e.g. sufficient income and...

Descripción completa

Detalles Bibliográficos
Autores principales: Op het Veld, Linda P.M., Ament, Bart H.L., van Rossum, Erik, Kempen, Gertrudis I.J.M., de Vet, Henrica C.W., Hajema, KlaasJan, Beurskens, Anna J.H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561574/
https://www.ncbi.nlm.nih.gov/pubmed/28818046
http://dx.doi.org/10.1186/s12877-017-0583-4
_version_ 1783257853606232064
author Op het Veld, Linda P.M.
Ament, Bart H.L.
van Rossum, Erik
Kempen, Gertrudis I.J.M.
de Vet, Henrica C.W.
Hajema, KlaasJan
Beurskens, Anna J.H.M.
author_facet Op het Veld, Linda P.M.
Ament, Bart H.L.
van Rossum, Erik
Kempen, Gertrudis I.J.M.
de Vet, Henrica C.W.
Hajema, KlaasJan
Beurskens, Anna J.H.M.
author_sort Op het Veld, Linda P.M.
collection PubMed
description BACKGROUND: Higher levels of frailty result in higher risks of adverse frailty outcomes such as hospitalisation and mortality. There are, however, indications that more factors than solely frailty play a role in the development of these outcomes. The presence of resources, e.g. sufficient income and good self-management abilities, might slow down the pathway from level of frailty to adverse outcomes (e.g. mortality). In the present paper we studied whether resources (i.e. educational level, income, availability of informal care, living situation, sense of mastery and self-management abilities) moderate the impact of the level of frailty on the adverse outcomes mortality, hospitalisation and the development of disability over a two-year period. METHODS: Longitudinal data on a sample of 2420 community-dwelling pre-frail and frail older people were collected. Participants filled out a questionnaire every six months, including measures of frailty, resources and outcomes. To study the moderating effects of the selected resources their interaction effects with levels of frailty on outcomes were studied by means of multiple logistics and linear regression models. RESULTS: Frail older participants had increased odds of mortality and hospitalisation, and had more deteriorating disability scores compared to their pre-frail counterparts. No moderating effects of the studied resources were found for the outcomes mortality and hospitalisation. Only for the outcome disability statistically significant moderating effects were present for the resources income and living situation, yet these effects were in the opposite direction to what we expected. Overall, the studied resources showed hardly any statistically significant moderating effects and the directions of the trends were inconsistent. CONCLUSIONS: Frail participants were more at risk of mortality, hospitalisation, and an increase in disability. However, we were unable to demonstrate a clear moderating effect of the studied resources on the adverse outcomes associated with frailty (among pre-frail and frail participants). More research is needed to increase insight into the role of moderating factors. Other resources or outcome measures should be considered.
format Online
Article
Text
id pubmed-5561574
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-55615742017-08-18 Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study Op het Veld, Linda P.M. Ament, Bart H.L. van Rossum, Erik Kempen, Gertrudis I.J.M. de Vet, Henrica C.W. Hajema, KlaasJan Beurskens, Anna J.H.M. BMC Geriatr Research Article BACKGROUND: Higher levels of frailty result in higher risks of adverse frailty outcomes such as hospitalisation and mortality. There are, however, indications that more factors than solely frailty play a role in the development of these outcomes. The presence of resources, e.g. sufficient income and good self-management abilities, might slow down the pathway from level of frailty to adverse outcomes (e.g. mortality). In the present paper we studied whether resources (i.e. educational level, income, availability of informal care, living situation, sense of mastery and self-management abilities) moderate the impact of the level of frailty on the adverse outcomes mortality, hospitalisation and the development of disability over a two-year period. METHODS: Longitudinal data on a sample of 2420 community-dwelling pre-frail and frail older people were collected. Participants filled out a questionnaire every six months, including measures of frailty, resources and outcomes. To study the moderating effects of the selected resources their interaction effects with levels of frailty on outcomes were studied by means of multiple logistics and linear regression models. RESULTS: Frail older participants had increased odds of mortality and hospitalisation, and had more deteriorating disability scores compared to their pre-frail counterparts. No moderating effects of the studied resources were found for the outcomes mortality and hospitalisation. Only for the outcome disability statistically significant moderating effects were present for the resources income and living situation, yet these effects were in the opposite direction to what we expected. Overall, the studied resources showed hardly any statistically significant moderating effects and the directions of the trends were inconsistent. CONCLUSIONS: Frail participants were more at risk of mortality, hospitalisation, and an increase in disability. However, we were unable to demonstrate a clear moderating effect of the studied resources on the adverse outcomes associated with frailty (among pre-frail and frail participants). More research is needed to increase insight into the role of moderating factors. Other resources or outcome measures should be considered. BioMed Central 2017-08-17 /pmc/articles/PMC5561574/ /pubmed/28818046 http://dx.doi.org/10.1186/s12877-017-0583-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Op het Veld, Linda P.M.
Ament, Bart H.L.
van Rossum, Erik
Kempen, Gertrudis I.J.M.
de Vet, Henrica C.W.
Hajema, KlaasJan
Beurskens, Anna J.H.M.
Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title_full Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title_fullStr Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title_full_unstemmed Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title_short Can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? A longitudinal study
title_sort can resources moderate the impact of levels of frailty on adverse outcomes among (pre-) frail older people? a longitudinal study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561574/
https://www.ncbi.nlm.nih.gov/pubmed/28818046
http://dx.doi.org/10.1186/s12877-017-0583-4
work_keys_str_mv AT ophetveldlindapm canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT amentbarthl canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT vanrossumerik canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT kempengertrudisijm canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT devethenricacw canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT hajemaklaasjan canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy
AT beurskensannajhm canresourcesmoderatetheimpactoflevelsoffrailtyonadverseoutcomesamongprefrailolderpeoplealongitudinalstudy