Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

BACKGROUND: Pre-implantation embryos exhibit sexual dimorphisms in both primates and rodents. To determine whether these differences reflected sex-biased expression patterns, we generated transcriptome profiles for six 40,XX, six 40,XY, and two 39,X mouse embryonic stem (ES) cells by RNA sequencing....

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Detalles Bibliográficos
Autores principales: Werner, Rachael J., Schultz, Bryant M., Huhn, Jacklyn M., Jelinek, Jaroslav, Madzo, Jozef, Engel, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561606/
https://www.ncbi.nlm.nih.gov/pubmed/28818098
http://dx.doi.org/10.1186/s13293-017-0150-x

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