Histone deacetylase-2 is involved in stress-induced cognitive impairment via histone deacetylation and PI3K/AKT signaling pathway modification

Exposure to chronic stress upregulates blood glucocorticoid levels and impairs cognition via diverse epigenetic mechanisms, such as histone deacetylation. Histone deacetylation can lead to transcriptional silencing of many proteins involved in cognition and may also cause learning and memory dysfunc...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Liu, Cui, Zhang, Ling, Qu, Chun-Hui, Sui, Xiao-Long, Zhu, Hua, Huang, Lan, Xu, Yan-Feng, Han, Yun-Lin, Qin, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561802/
https://www.ncbi.nlm.nih.gov/pubmed/28656275
http://dx.doi.org/10.3892/mmr.2017.6840

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