Cargando…

Antidepressant effects of Kai-Xin-San in fluoxetine-resistant depression rats

This study aimed to investigate the antidepressant effect and the mechanism of action of Kai-Xin-San (KXS) in fluoxetine-resistant depressive (FRD) rats. Two hundred male Wistar rats weighing 200±10 g were exposed to chronic and unpredictable mild stresses (CUMS) for 4 weeks and given fluoxetine tre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, X.Z., Wang, D.X., Lu, Y.P., Yuan, S., Liu, P., Hu, Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561807/ https://www.ncbi.nlm.nih.gov/pubmed/28832762 http://dx.doi.org/10.1590/1414-431X20176161

Ejemplares similares

MiR-1281 is involved in depression disorder and the antidepressant effects of Kai-Xin-San by targeting ADCY1 and DVL1
por: Chen, Chao, et al.
Publicado: (2023)

Kai Xin San ameliorates scopolamine-induced cognitive dysfunction
por: Xu, Yu-Min, et al.
Publicado: (2019)

Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation
por: Dong, Xian-Zhe, et al.
Publicado: (2019)

Behavioral and biochemical effects of a formulation of the traditional Chinese medicine, Kai-Xin-San, in fatigued rats
por: HU, YUAN, et al.
Publicado: (2013)

Kai-Xin-San, a traditional Chinese medicine formulation, exerts antidepressive and neuroprotective effects by promoting pCREB upstream pathways
por: Dong, Xian-Zhe, et al.
Publicado: (2016)

Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer’s Disease
por: Luo, Yunxia, et al.
Publicado: (2020)

A Chinese herbal decoction, reformulated from Kai-Xin-San, relieves the depression-like symptoms in stressed rats and induces neurogenesis in cultured neurons
por: Yan, Lu, et al.
Publicado: (2016)

Corrigendum: Systems pharmacology approach to investigate the mechanism of Kai-Xin-San in Alzheimer’s disease
por: Luo, Yunxia, et al.
Publicado: (2023)

Kai-Xin-San Inhibits Tau Pathology and Neuronal Apoptosis in Aged SAMP8 Mice
por: Jiao, Ya-Nan, et al.
Publicado: (2022)

A Comparative Study of Serum Pharmacochemistry of Kai-Xin-San in Normal and AD Rats Using UPLC-LTQ-Orbitrap-MS
por: Yang, Lin, et al.
Publicado: (2022)

Kai-Xin-San, a Chinese Herbal Decoction, Accelerates the Degradation of β-Amyloid by Enhancing the Expression of Neprilysin in Rats
por: Wang, Na, et al.
Publicado: (2020)

Study on the Multitarget Synergistic Effects of Kai-Xin-San against Alzheimer's Disease Based on Systems Biology
por: Guo, Sirui, et al.
Publicado: (2019)

Kai-Xin-San Protects Depression Mice Against CORT-Induced Neuronal Injury by Inhibiting Microglia Activation and Oxidative Stress
por: Bai, Guiqin, et al.
Publicado: (2022)

A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats
por: Zhu, Kevin Yue, et al.
Publicado: (2012)

Classic Prescription, Kai-Xin-San, Ameliorates Alzheimer's Disease as an Effective Multitarget Treatment: From Neurotransmitter to Protein Signaling Pathway
por: Guo, Sirui, et al.
Publicado: (2019)

Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway
por: Su, ShiJie, et al.
Publicado: (2023)

Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus
por: Zhu, Yue, et al.
Publicado: (2017)

Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation
por: Wang, Na, et al.
Publicado: (2017)

Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease
por: Yi, Pengji, et al.
Publicado: (2020)

Jia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice
por: Zhang, Xiaolu, et al.
Publicado: (2023)

Kai-Xin-San Attenuates Doxorubicin-Induced Cognitive Impairment by Reducing Inflammation, Oxidative Stress, and Neural Degeneration in 4T1 Breast Cancer Mice
por: Lyu, Wenjiao, et al.
Publicado: (2021)

A Modified Chinese Herbal Decoction (Kai-Xin-San) Promotes NGF-Induced Neuronal Differentiation in PC12 Cells via Up-Regulating Trk A Signaling
por: Yan, Lu, et al.
Publicado: (2017)

Kai-Xin-San, a Chinese Herbal Decoction Containing Ginseng Radix et Rhizoma, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria, Stimulates the Expression and Secretion of Neurotrophic Factors in Cultured Astrocytes
por: Zhu, Kevin Yue, et al.
Publicado: (2013)

Chinese Medicine Formula Kai-Xin-San Ameliorates Neuronal Inflammation of CUMS-Induced Depression-like Mice and Reduces the Expressions of Inflammatory Factors via Inhibiting TLR4/IKK/NF-κB Pathways on BV2 Cells
por: Qu, Suchen, et al.
Publicado: (2021)

Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of Aβ(1-42) Induced Cognitive Deficit Mice
por: Zhu, Yue, et al.
Publicado: (2019)

Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression
por: Ramsteijn, Anouschka S, et al.
Publicado: (2020)

Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates
por: Guo, M, et al.
Publicado: (2014)

Olanzapine and fluoxetine combination in severe or resistant depression
por: Haridas, R.M., et al.
Publicado: (2003)

Antidepressant-like effects of Chaihu-Shugan-San via SAPK/JNK signal transduction in rat models of depression
por: Li, Yun-Hui, et al.
Publicado: (2014)

Metabolism and Pharmacokinetics of San-Huang-Xie-Xin-Tang, a Polyphenol-Rich Chinese Medicine Formula, in Rats and Ex-Vivo Antioxidant Activity
por: Shia, Chi-Sheng, et al.
Publicado: (2011)

Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis
por: Liu, Kao-Hui, et al.
Publicado: (2014)

Evaluation of the antidepressant activity of Moringa oleifera alone and in combination with fluoxetine
por: Kaur, Ginpreet, et al.
Publicado: (2015)

Fibroblast growth factor 2 is necessary for the antidepressant effects of fluoxetine
por: Simard, Stephanie, et al.
Publicado: (2018)

Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID-19
por: Mahdi, Mohamed, et al.
Publicado: (2022)

Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation
por: Ma, Min, et al.
Publicado: (2016)

Survey of Two New (Kai 1 and Kai 2) and Other Blood Groups in Dogs of North America
por: Euler, C.C., et al.
Publicado: (2016)

Meta-analysis on the efficacy and tolerability of the augmentation of antidepressants with atypical antipsychotics in patients with major depressive disorder
por: Wen, X.J., et al.
Publicado: (2014)

The Use of San-Huang-Xie-Xin-Tang Reduces the Mortality Rate among Breast Cancer Patients
por: Winardi, Daniel, et al.
Publicado: (2023)

Xin hua jing /
Publicado: (1982)

Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex
por: Yan, Lijing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kb163dhqikp9nhdjo91hanrr7k