Methotrexate associated to lipid core nanoparticles improves cardiac allograft vasculopathy and the inflammatory profile in a rabbit heart graft model

Coronary allograft vasculopathy is an inflammatory-proliferative process that compromises the long-term success of heart transplantation and has no effective treatment. A lipid nanoemulsion (LDE) can carry chemotherapeutic agents in the circulation and concentrates them in the heart graft. The aim o...

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Detalles Bibliográficos
Autores principales: Fiorelli, A.I., Lourenço-Filho, D.D., Tavares, E.R., Carvalho, P.O., Marques, A.F., Gutierrez, P.S., Maranhão, R.C., Stolf, N.A.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561808/
https://www.ncbi.nlm.nih.gov/pubmed/28832763
http://dx.doi.org/10.1590/1414-431X20176225

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