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Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination

Repair of DNA interstrand crosslinks (ICLs) predominantly involves the Fanconi anemia (FA) pathway and homologous recombination (HR). The HR repair system eliminates DNA double strand breaks (DSBs) that emerge during ICLs removal. The current study presents a novel cell line, CL-V8B, representing a...

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Detalles Bibliográficos
Autores principales:	Gorniewska, Aleksandra M., Kluzek, Katarzyna, Gackowska, Lidia, Kubiszewska, Izabela, Zdzienicka, Malgorzata Z., Bialkowska, Aneta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561886/ https://www.ncbi.nlm.nih.gov/pubmed/28627616 http://dx.doi.org/10.3892/mmr.2017.6781

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