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Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase

Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT), and so remains...

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Detalles Bibliográficos
Autores principales:	Chang, Kwang-Yu, Hsu, Tsung-I., Hsu, Che-Chia, Tsai, Shan-Yin, Liu, Jr-Jiun, Chou, Shao-Wen, Liu, Ming-Sheng, Liou, Jing-Ping, Ko, Chiung-Yuan, Chen, Kai-Yun, Hung, Jan-Jong, Chang, Wen-Chang, Chuang, Cheng-Keng, Kao, Tzu-Jen, Chuang, Jian-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561972/ https://www.ncbi.nlm.nih.gov/pubmed/28822335 http://dx.doi.org/10.1016/j.redox.2017.08.005

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