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P18 peptide, a functional fragment of pigment epithelial-derived factor, inhibits angiogenesis in hepatocellular carcinoma via modulating VEGF/VEGFR2 signalling pathway
The P18 peptide is a functional fragment of pigment epithelial-derived factor (PEDF), which is an endogenic angiogenesis inhibitor. This study sought to determine the anti-angiogenic bioactivity of the P18 peptide in hepatocellular carcinoma (HCC) and to elucidate the underlying mechanism. Xenograft...
Autores principales: | Wang, Xin, Xiu, Peng, Wang, Fuhai, Zhong, Jingtao, Wei, Honglong, Xu, Zongzhen, Liu, Feng, Li, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562001/ https://www.ncbi.nlm.nih.gov/pubmed/28627623 http://dx.doi.org/10.3892/or.2017.5719 |
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