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Rho-kinase signaling pathway promotes the expression of PARP to accelerate cardiomyocyte apoptosis in ischemia/reperfusion

It has been previously reported that Rho-kinase (ROCK) and poly ADP-ribose polymerase (PARP) serve critical roles in myocardial ischemia/reperfusion (I/R) injury. Studies have additionally demonstrated that the activation of ROCK and the expression of PARP are increased in I/R. However, the effect a...

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Detalles Bibliográficos
Autores principales:	Bian, Hongjun, Zhou, Yi, Yu, Bin, Shang, Deya, Liu, Fuli, Li, Bin, Qi, Jianni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562013/ https://www.ncbi.nlm.nih.gov/pubmed/28656263 http://dx.doi.org/10.3892/mmr.2017.6826

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