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Transcription factor 7 like 2 promotes oligodendrocyte differentiation and remyelination

Transcription factor 7 like 2 (TCF7L2, also termed TCF4), is a Wnt effector induced transiently in the oligodendroglial lineage. The current well accepted hypothesis is that TCF7L2 inhibits oligodendrocyte differentiation and remyelination through canonical Wnt/β-catenin signaling. However, recent s...

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Detalles Bibliográficos
Autores principales: Weng, Chao, Ding, Man, Fan, Shanghua, Cao, Qian, Lu, Zuneng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562062/
https://www.ncbi.nlm.nih.gov/pubmed/28656232
http://dx.doi.org/10.3892/mmr.2017.6843