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Effect of the spinal apelin-APJ system on the pathogenesis of chronic constriction injury-induced neuropathic pain in rats

Apelin is hypothesized to serve a dual function in pain processing. Spinal administration of apelin induces hyperalgesia, while opioid receptors are implicated in the antinociceptive effects of apelin in acute nociceptive models. However, whether the apelin-apelin receptor (APJ) system is involved i...

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Detalles Bibliográficos
Autores principales: Xiong, Qingming, He, Wanyou, Wang, Hanbing, Zhou, Jun, Zhang, Yajun, He, Jian, Yang, Chengxiang, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562064/
https://www.ncbi.nlm.nih.gov/pubmed/28627589
http://dx.doi.org/10.3892/mmr.2017.6734