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Inhibition of autophagy by berberine enhances the survival of H9C2 myocytes following hypoxia

Hypoxia may induce apoptosis and autophagy to promote cardiomyocyte injury. The present study investigated the effect of berberine, a natural extract of Rhizoma Coptidis, on hypoxia-induced autophagy and apoptosis in the H9c2 rat myocardial cell line. Expression levels of apoptosis and autophagy mar...

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Detalles Bibliográficos
Autores principales: Jia, Zhuyin, Lin, Lu, Huang, Shanjun, Zhu, Zhouyang, Huang, Weijian, Huang, Zhouqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562068/
https://www.ncbi.nlm.nih.gov/pubmed/28627660
http://dx.doi.org/10.3892/mmr.2017.6770