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Wnt/β-catenin signaling pathway activation reverses gemcitabine resistance by attenuating Beclin1-mediated autophagy in the MG63 human osteosarcoma cell line

Anaberrant Wnt/β-catenin signaling pathway is frequently implicated in tumorigenesis. However, whether the Wnt/β-catenin pathway plays a role in resistance to antitumor chemotherapy drugs remains unknown. In the present study, the process of autophagy was assessed following overexpression of the aut...

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Detalles Bibliográficos
Autores principales:	Tao, Hao, Chen, Feng, Liu, Haifei, Hu, Yanling, Wang, Yingzhen, Li, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562091/ https://www.ncbi.nlm.nih.gov/pubmed/28656199 http://dx.doi.org/10.3892/mmr.2017.6828

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